MINING METAGENOMES AND METATRANSCRIPTOMES UNVEILS VIRUSES ASSOCIATED WITH CUTANEOUS SQUAMOUS CELL CARCINOMA IN HEMATOPOIETIC STEM CELL TRANSPLANT RECIPIENTS

ABSTRACT We investigated the presence of viral DNA and RNA in cutaneous squamous cell carcinoma (cSCC) tumor and normal tissues from nine individuals with a history of hematopoietic stem cell transplantation (HCT).Microbiome quantification through DNA and RNA sequencing (RNA-seq) revealed the presence of 18 viruses in both tumor and normal tissues.

Systemic lupus erythematosus (SLE) represents a challenging autoimmune disease from a clinical perspective because of its varied forms of presentation.Although terracotta charger broad-spectrum steroids remain the standard treatment for SLE, they have many side effects and only provide temporary relief from the symptoms of the disease.Thus, gaining

Wheat brown rust called the fungus PucciniatriticinaRob.exDesm.f.sp.triticiErikss.etHenn.is the main disease of the varieties of winter soft wheat (TriticumaestivumL.), grown in the south of Russia.The purpose of the study was to give the characteristics of the resistance to brown rust of 12 varieties of winter soft wheat during the period activeca

activecare spitfire The past decade has seen an increasing number of applications of deep learning (DL) techniques to biomedical fields, especially in neuroimaging-based analysis.Such DL-based methods are generally data-intensive and require a large number of training instances, which might be infeasible to acquire from a single acquisition site, e